Auto commit data after update

Is there any way to enable auto commit data rather than having to use control-enter or click on the POST button after every change?

I suppose you aren't really talking about transactions (auto-commit is normally the default in MySQL and there's no specific GUI to change that from within HeidiSQL) but about sending a query to the server every time you edit a single cell. Nope, there's no such feature. HeidiSQL assumes you might want to edit more that one column (or even cancel current edit).